Scientists have reversed paralysis

RbR
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Edited Date/Time 11/22/2012 4:26pm

Jasper the dachshund walking again


Scientists have reversed paralysis in dogs after injecting them with cells grown from the lining of their nose.

The pets had all suffered spinal injuries which prevented them from using their back legs.

The Cambridge University team is cautiously optimistic the technique could eventually have a role in the treatment of human patients.

The study is the first to test the transplant in "real-life" injuries rather than laboratory animals.

Read More :: http://www.bbc.co.uk/news/health-20365355
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motosmith
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11/19/2012 8:40am
That's really cool.

I'm amazed doctors haven't figured out a fix by now. It seems it would be way easier than it is.
11/19/2012 8:55am
It is very very cool but it's not going to be happening to humans anytime soon. Far too many naysayers in the way of real progress. We all know the massive amount of fighters against real stem cell research and it's use in us, fucking numpties - probably the same bunch of people against assisted suicide - most of whom have an opinion but very few if any have actual experience of why it is useful.
nytsmaC
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11/19/2012 9:00am
I hope this thread doesn't turn into a religious/political debate, but it would sure be nice if the efforts to help the desperate people in need weren't stood in the way of.

The Shop

Tbteam
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11/19/2012 9:23am
Developments like this one are ongoing and relatively common. This is good news for people who are not yet injured, but in my opinion will have little bearing on the lives of those who have been battling paralysis for some time.

Atrophied muscles do not return, they calcify. This would be the hurdle that mutes the exciting developments that are making the news every few months.

I wish this would all be figured out.
Falcon
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11/19/2012 10:57am
Cells grown from the lining of the dog's own nose? What can the naysayers possibly have a problem with this time? "Sure the dog can walk again, but he has a bloody nose! Call PETA!!!" ?
robkinuk
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11/19/2012 11:04am
There was a major piece on this in the BBC evening news bulitin. Results for dog looked fantastic but scientists at Cambridge University UK doing research did say there are major differences in the way a dog (four legged animal) would react to this treatment compared to a human, but at least it's a big step in the right direction.
FroDiddy
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11/19/2012 11:16am Edited Date/Time 11/19/2012 11:16am
It is very very cool but it's not going to be happening to humans anytime soon. Far too many naysayers in the way of real progress...
It is very very cool but it's not going to be happening to humans anytime soon. Far too many naysayers in the way of real progress. We all know the massive amount of fighters against real stem cell research and it's use in us, fucking numpties - probably the same bunch of people against assisted suicide - most of whom have an opinion but very few if any have actual experience of why it is useful.
I share your frustration.

It's always encouraging to hear stories like this. I remember the one about the mouse (or rat) a few months back.
Spergen
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11/19/2012 11:45am
I know this isn't going to be very popular but my sister is a Dr and she says we owe a lot of our recent medical knowledge to the research the Nazis did in WW2 !! But yes far too many do gooders all over the place, if people are of sound mind and want to be involved with research into there particular situation why stop them.
mac3-d
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11/19/2012 12:57pm
i heard from a friend , that in japan they deliberately break the backs of monkeys in different places (up/down the spinal cord), then after treatment they are able to move / walk again. don't know any other details but he was in Switzerland for treatment which was unsuccessful & is hoping for the Japaneese will make the treatment available for humans soon (don't think it has been licensed by their goverment yet for human trials)
"Atrophied muscles do not return, they calcify" not sure about this but he gets a physio & hydro pool therapy to keep movement in hips &legs (also to keep muscles in shape)
DrSweden
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11/19/2012 2:01pm
Very cool! One small step in the right direction, it's just a matter of time (which some might not have, but anyway). No need to worry about those being negative towards stem cell research, those smart/creative people from the US that are being hold back, are in some cases able to work in Europe, and that work will benefit even the negatives on home soil in the end.

Despite the bigger task to repair old injuries, this will benefit them in the end as well, I'm sure.
ocscottie
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11/19/2012 2:45pm
Just for the record, they also did this quite a few (many) years ago w/ cats.

Get this, even almost 28 years ago when my accident happened, in 1985 they were filling our minds w/ hope, saying that a cure was only 10 years away, and ill repeat myself, this was 28 years ago! They had little doubt that it wasnt far off at all. Now imagine being just 15 years old and hearing that, while trying to "adjust" and "cope" with everything else going on.

...and in no way am i discrediting how far things have come or what they are doing, just trying to give you guys a little "first hand" experience and perspective from someone who has been though this. Also, way more importantly, not being able to "walk" is by far the least frustrating aspect of suffering an SCI. Those more familiar w/ it, or have been through this, know exactly what im talking about. btw: i am referring to "bodily functions" Dizzy
ocscottie
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11/19/2012 2:50pm Edited Date/Time 11/19/2012 2:54pm
Tbteam wrote:
Developments like this one are ongoing and relatively common. This is good news for people who are not yet injured, but in my opinion will have...
Developments like this one are ongoing and relatively common. This is good news for people who are not yet injured, but in my opinion will have little bearing on the lives of those who have been battling paralysis for some time.

Atrophied muscles do not return, they calcify. This would be the hurdle that mutes the exciting developments that are making the news every few months.

I wish this would all be figured out.
Mark, i am sure you know exactly where i am coming from in my above post.

..and i dont mean to or hope that what i said comes off sounding bitter, i am just trying to convey the reality of the situation.
GuyB
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11/19/2012 2:58pm
Spergen wrote:
I know this isn't going to be very popular but my sister is a Dr and she says we owe a lot of our recent medical...
I know this isn't going to be very popular but my sister is a Dr and she says we owe a lot of our recent medical knowledge to the research the Nazis did in WW2 !! But yes far too many do gooders all over the place, if people are of sound mind and want to be involved with research into there particular situation why stop them.
Everyone's entitled to their own stupid opinion. Even your sister.
gotwings
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11/19/2012 3:03pm
I had reverse paralysis once, but it subsided once the drugs were out of my system...
11/19/2012 3:06pm
Scottie, I follow the rutgers care cure forums pretty closely ever since my injury... I hear what you said above alot. I fear having to say the exact same thing someday. I hope Im wrong. There are alot of things going on in other countries right now though. Sucks that the FDA is such a hassle and costly approach to bringing studies to the USA.
Ive been reading about a few good therapies in China, Brazil, and Switzerland, all on chronics and all showing progress and safety. Still gotta be a good few years from being available to the public i assume. Which is crazy to me because they are essentially transplanting cells. Transplanting hearts and other organs is completely fine, but dont fuck around with cells. Evil
Imagine if Nasa spent that mars mission money on this. Or maybe they will bring the cure back home from mars! Woohoo
ocscottie
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11/19/2012 3:16pm
Cure Care is an AWESOME resource and has an administration of some really great people, that Dr Wise Young is an awesome dude, and the nurses there that help out on the forum are really good people, have helped me out quite a few times.

btw: i really like the "equipment" forum section, you get to see some cool stuff, and the best place to get "real world" experience.

I also frequent the "pain" section, but can only take it in small doses, even just talking about the whole "neuropathic" (phantom pains) makes my shit flare up even worse than it normally is. I swear the only way to really put it into words is imagine your feet sitting in a pool of hot lava, and the flesh is just melting from your bones.....uughhh not fun at all, and the biggest bummer is that ALL the meds that work for so many people, give me really bad side affects once i reach the doseage where they start to help w/ the pain themselves. Frustrating to say the least! and i have tried them all. Dizzy
FastEddy
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11/19/2012 3:18pm Edited Date/Time 11/19/2012 3:26pm
Spergen wrote:
I know this isn't going to be very popular but my sister is a Dr and she says we owe a lot of our recent medical...
I know this isn't going to be very popular but my sister is a Dr and she says we owe a lot of our recent medical knowledge to the research the Nazis did in WW2 !! But yes far too many do gooders all over the place, if people are of sound mind and want to be involved with research into there particular situation why stop them.
Operation ''Paper Clip'' brought those Doctors & Scientists and their technology over here after WWII.
But lets just say,they toned it down a bit....and worked closely with our military and they weren't Nazi's anymore at that time lol. They did indeed contribute medically to some things. But we never really worked with adrenaline toning a society and our armies and all that other crazy shit Hitler did.
ocscottie
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11/19/2012 3:52pm
gotwings wrote:
I had reverse paralysis once, but it subsided once the drugs were out of my system...
DUDE! after im done eating ill share the story about being able to move my legs! happened one night back in the early 90's (party days) and took some really high grade (ie: very powerful) Ecstasy i got from Texas, i will never forget that night as long as i live!
11/19/2012 3:59pm
ocscottie wrote:
Cure Care is an AWESOME resource and has an administration of some really great people, that Dr Wise Young is an awesome dude, and the nurses...
Cure Care is an AWESOME resource and has an administration of some really great people, that Dr Wise Young is an awesome dude, and the nurses there that help out on the forum are really good people, have helped me out quite a few times.

btw: i really like the "equipment" forum section, you get to see some cool stuff, and the best place to get "real world" experience.

I also frequent the "pain" section, but can only take it in small doses, even just talking about the whole "neuropathic" (phantom pains) makes my shit flare up even worse than it normally is. I swear the only way to really put it into words is imagine your feet sitting in a pool of hot lava, and the flesh is just melting from your bones.....uughhh not fun at all, and the biggest bummer is that ALL the meds that work for so many people, give me really bad side affects once i reach the doseage where they start to help w/ the pain themselves. Frustrating to say the least! and i have tried them all. Dizzy
Eh, i dont have the hot lava, just the pins and needles. Ive recently been terrified of needles, and I think that is why. And its a come and go kind of thing with me too. Whats really trippy is that i can "activate" it by touching certain spots.

But yes, Care Cure forums was a genius idea. And Dr. Wise Young is on to some really awesome stuff. Hope you are following that trial still. Im pretty sure alot of those patients were older (but young at heart fellas like yourself Wink ) and quite old injuries with some positive results at early and low dosage stages. I guess the scary part is, one patient said the neuropathic pain increased, but also said the motor and sensory return was worth it. Sideways
11/19/2012 4:01pm
gotwings wrote:
I had reverse paralysis once, but it subsided once the drugs were out of my system...
ocscottie wrote:
DUDE! after im done eating ill share the story about being able to move my legs! happened one night back in the early 90's (party days)...
DUDE! after im done eating ill share the story about being able to move my legs! happened one night back in the early 90's (party days) and took some really high grade (ie: very powerful) Ecstasy i got from Texas, i will never forget that night as long as i live!
HAHA. Maybe you should share that with some scientists! Could you imagine the cure has been a stem cell ecstasy blend all along. Woohoo
Tbteam
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11/19/2012 4:24pm
Tbteam wrote:
Developments like this one are ongoing and relatively common. This is good news for people who are not yet injured, but in my opinion will have...
Developments like this one are ongoing and relatively common. This is good news for people who are not yet injured, but in my opinion will have little bearing on the lives of those who have been battling paralysis for some time.

Atrophied muscles do not return, they calcify. This would be the hurdle that mutes the exciting developments that are making the news every few months.

I wish this would all be figured out.
ocscottie wrote:
Mark, i am sure you know exactly where i am coming from in my above post. ..and i dont mean to or hope that what i...
Mark, i am sure you know exactly where i am coming from in my above post.

..and i dont mean to or hope that what i said comes off sounding bitter, i am just trying to convey the reality of the situation.
No, Scottie. I get your perspective completely. Same thing with DB. Whn he got hurt, I remember the talk of a cure in 5-10 years. I kept thinking, " will he still have a chance to race by then"? Seems foolish now, but I really believed.
11/19/2012 5:05pm
It is very very cool but it's not going to be happening to humans anytime soon. Far too many naysayers in the way of real progress...
It is very very cool but it's not going to be happening to humans anytime soon. Far too many naysayers in the way of real progress. We all know the massive amount of fighters against real stem cell research and it's use in us, fucking numpties - probably the same bunch of people against assisted suicide - most of whom have an opinion but very few if any have actual experience of why it is useful.
This is pretty much the way I look at it.
ocscottie
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11/19/2012 5:18pm
Tbteam wrote:
No, Scottie. I get your perspective completely. Same thing with DB. Whn he got hurt, I remember the talk of a cure in 5-10 years. I...
No, Scottie. I get your perspective completely. Same thing with DB. Whn he got hurt, I remember the talk of a cure in 5-10 years. I kept thinking, " will he still have a chance to race by then"? Seems foolish now, but I really believed.
Yea Mark i knew you would "get" exactly what i was saying, the 2nd part of that post of mine wasnt directed at you Cool
ocscottie
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11/19/2012 5:40pm
It is still really amazing how far we have come since then, not so much on the "research or cure" side of things, but the awareness is almost mind blowing!

Just imagine having to worry EVERYWHERE you went whether it was going to be accessible or not? and 7 times out of 10, it wasnt! Remember this was all before the ADA (Americans with Disabilities Act) came into affect.

Get this, one of the requirements for someone my injury level was not allowed to be discharged from the hospital/rehab center until you could jump up a curb. There was a whole test you had to pass, such as be able to ride a wheelie the length of the hallway, of course i loved that one! In fact while i was still in a back/neck brace wheelie bars were a requirement on my chair so i didnt loop out and hurt my spine before the surgery completely healed, well i ended up breaking them off from "trying" to wheelie lol

I raised so much hell at Santa Clara Valley med Center (same place DB and Magoo all did our rehab, at the time it was the #1 place in CA for SCI) My rehab therapist was a way cool chick, she found me a hospital chair that had big wide treaded tires on them, which she later regretted, my room was at the end of a long hallway and i would go WFO down the hall and lockup the brakes and fully brakeslide into my room, well it left huge tire marks on the floor leading into my room about 6-7ft long lol The janitor guy cussed me out everytime he had to come wax the floor Laughing

My now infamous motto: "You can take the man out of MX, but you can NEVER take the MX out of the man!" is the truth!

..the end to yet another ramble brought to you by RedBull! Luckily it is time for Monday Night Football....or i would prob still be typing Laughing
ocscottie
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11/19/2012 5:52pm
HAHA. Maybe you should share that with some scientists! Could you imagine the cure has been a stem cell ecstasy blend all along. Woohoo
Stephen, dude it is SO mind blowing most think i am either making it up, or it was some sorta drug induced hallucination, luckily there was friends who witnessed it that were "straight" at the time. It brought tears to most of them there to witness it, and it is 100% the Gods honest truth, a lot like some of the wild stories i have told about the times i shared with Magoo. Cool

I will elaborate more after the game. GO 9ers!!!
6-wheelz
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11/19/2012 6:07pm
ocscottie wrote:
Cure Care is an AWESOME resource and has an administration of some really great people, that Dr Wise Young is an awesome dude, and the nurses...
Cure Care is an AWESOME resource and has an administration of some really great people, that Dr Wise Young is an awesome dude, and the nurses there that help out on the forum are really good people, have helped me out quite a few times.

btw: i really like the "equipment" forum section, you get to see some cool stuff, and the best place to get "real world" experience.

I also frequent the "pain" section, but can only take it in small doses, even just talking about the whole "neuropathic" (phantom pains) makes my shit flare up even worse than it normally is. I swear the only way to really put it into words is imagine your feet sitting in a pool of hot lava, and the flesh is just melting from your bones.....uughhh not fun at all, and the biggest bummer is that ALL the meds that work for so many people, give me really bad side affects once i reach the doseage where they start to help w/ the pain themselves. Frustrating to say the least! and i have tried them all. Dizzy
C6 C7 quad incomplete 5yrs now,Know exactly what you talking about. Cure products donate lots of money to reasearch, so glad not to have the pain issues you guys talk about.
Spergen
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11/19/2012 6:17pm
FastEddy wrote:
Operation ''Paper Clip'' brought those Doctors & Scientists and their technology over here after WWII. But lets just say,they toned it down a bit....and worked closely...
Operation ''Paper Clip'' brought those Doctors & Scientists and their technology over here after WWII.
But lets just say,they toned it down a bit....and worked closely with our military and they weren't Nazi's anymore at that time lol. They did indeed contribute medically to some things. But we never really worked with adrenaline toning a society and our armies and all that other crazy shit Hitler did.
In no way am i condoning what they did, in fact I think they should of hung at the gallows with the rest of them. (have you read what they did to twins in the name of science ? makes you cry) But we did use there research and in many cases advanced medical solutions of the time and beyond.

Anyway back on topic, from seeing the article on the news they managed to reconnect the nerves along the spine so front and back legs worked together but are no closer to linking it back to the brain. But on the bright side every little step is a step closer. Think we should all cancel 1 nuclear sub each and throw a few billion at it, would definitely help more people.
ocscottie
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11/19/2012 6:36pm
6-wheelz wrote:
C6 C7 quad incomplete 5yrs now,Know exactly what you talking about. Cure products donate lots of money to reasearch, so glad not to have the pain...
C6 C7 quad incomplete 5yrs now,Know exactly what you talking about. Cure products donate lots of money to reasearch, so glad not to have the pain issues you guys talk about.
Welcome to the "unfortunate" club brother! Cool

How incomplete are you? that could have a lot to do with it. then again i didnt have many pain issues at all for about 20 years or so, a little "phantom" pains but nothing like it is now, and has gotten progressively worse as each year goes by. I do need to have another really gnarly surgery though, after 28 years the rods i have, have totally worn out the 2 vertebrae below them. That could be a major cause of my pain problems, but the surgery i need scares the living shit out of me and i have been putting it off for many years now....but know i have to have it done "someday".

Damn, there is way to many of "us" here on the board. Dizzy

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